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Single cell microdosimetric studies comparing ideal and measured nanosecond pulsed electric fields

TitleSingle cell microdosimetric studies comparing ideal and measured nanosecond pulsed electric fields
Publication TypePresentazione a Congresso
Year of Publication2013
AuthorsDenzi, A., Merla Caterina, Palego C., Apollonio F., Hwang J.C.M., and Liberti M.
Conference NameIEEE MTT-S International Microwave Symposium Digest
KeywordsElectric field measurement, Electric fields, Ideal and real nsPEFs, Intracellular manipulation, Micro-chambers, Micro-dosimetry, Microdosimetric study, molecular biology, Nanosecond pulsed electric fields, Nanosecond time scale, pulsed electric field
Abstract

Recently, the promising effects induced by pulsed electric fields with high intensity and short duration have been highlighted. At the nanosecond time scale, electric pulse targets become both the plasmatic membrane and the sub-cellular structures (possibility of intracellular manipulation). In this paper, a circuit cell model with nucleus is presented, validated and used in order to assess the different cellular and sub-cellular (i.e. nucleus) effects, comparing ideal nanosecond pulsed electric fields (nsPEFs) waveforms with the ones measured from a planar, broadband matched microchamber. © 2013 IEEE.

URLhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84893292251&doi=10.1109%2fMWSYM.2013.6697655&partnerID=40&md5=2591d4898eb7c48d9decd16d774412da
DOI10.1109/MWSYM.2013.6697655
Citation KeyDenzi2013